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This process, triggered by lipid peroxidation and excessive reactive oxygen species (ROS) accumulation, offers a novel perspective on the pathophysiology and potential therapeutic approaches for CHD (5, 6)

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2.9 Collection of the brain tissue samples Rats were euthanized through CO 2 asphyxiation within a glass chamber ( 2.10 Enzyme-linked Immunosorbent assays Brain tissues were harvested from all animals and subsequently homogenized using a neuronal lysis buffer

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Palmitoyl Pentapeptide-4 (Matrixyl): Both stimulate collagen, but Pal-GHK acts via GHK mimicry, while Matrixyl mimics a different collagen fragment, offering slightly varied ECM effects

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