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Because using primary hLECs was cumbersome due to their limited availability, we utilized the SRA-hLECs and, to generalize our findings, we included primary rLECs as a model system

However, scientific integrity demands recognition of the limits of current evidence

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(Oxford, England) 11 , 16871689 (1996)

Many children with ASD have poor transsulfuration and methylation they cant make glutathione and even worse, they cant activate many neurotransmitters in the brain

These cytokines can promote cognitive dysfunction as they are able to disrupt the blood-brain barrier (BBB), allowing proinflammatory cytokines (52), cells (such as dendritic, B cells, and T cells) (52), and gut microbes or toxins (355) to translocate into the brain and promote inflammation ( Figure 10 )