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Several international guidelines (from the National Institute for Health and Care Excellence, the New Zealand Ministry of Health, the Royal Australian College of General Practitioners, and the Haute Authorit de Sant de France) advise that e-cigarettes may be used for cessation in certain cases but that information should be provided on the risks and uncertainties, including that e-cigarettes are not licensed medicines in most jurisdictions, and that there is a lack of evidence on long-term harms.95 , 97 99 The Australian and French guidelines suggest that other therapies should be considered first.97 , 99 The United States Preventive Services Task Force judged that the evidence on e-cigarettes was insufficient and recommends directing patients to interventions with proven effectiveness and safety.94 Gaps in knowledge Large comparative trials101 will likely refine future recommendations
Am J Physiol Regul Integr Comp Physiol 314: R834R847, 2018
For instance, a 60-year-old smoker typically has the health profile of a 70-year-old non-smoker
Additional Medications to Treat Tobacco Addiction Although the major focus of pharmacological treatments for tobacco addiction has been nicotine replacement, other treatments are also being studied
Tragically, smoking significantly elevates the likelihood of experiencing a stroke, a severe condition where blood flow to the brain is interrupted, leading to potentially permanent brain damage and disability
