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Walker Smith Sports Editor Walker Smith is a former managing editor in the digital department of The State Press and is an ASU alum

Because regulatory approval requires: robust human clinical trials demonstrated efficacy established long-term safety These data are currently lacking

Insufficiency can lead to fatigue and weight gain, and an injection of vitamin B12 can increase energy and help with gastrointestinal issues

However, three major reviews didnt show sufficient evidence to support this claim (14, 15, 16)

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While hyperhomocysteinemia may increase the risk of cognitive impairment and age-related neurodegenerative disease (e.g., Alzheimers disease), it is not clear whether vitamin B 12 deficiency contributes to the risk of dementia in the elderly