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However, supplementation should always follow the "Live with Intention" framework: foundations first, then targeted support

The depletion of glutathione leads to the (i) release of inflammatory cytokines, (ii) the formation of free radicals, and (iii) the inhibition of some cell functions, all of which have been known to cause many chronic degenerative diseases and functional loss with ageing

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Curcumin is an APE1 redox inhibitor and exhibits an antiviral activity against KSHV replication and pathogenesis

This is because hair follicle regeneration is a dynamic process critically reliant on energy metabolism and cellular metabolic reprogramming, wherein the fate of HFSCs is determined by the coordinated regulation of glucose, lipid, and amino acid metabolism (Kim et al., 2020)