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Clin Cancer Res 24(2):341-350, 2018
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After 5 days of treatment, organoid proliferation was quantified via a BrdU colorimetric immunoassay from Roche (Cat
ROS are a collection of oxidative molecules with various biological functions, including the superoxide anion (O 2 ), hydrogen peroxide (H 2 O 2 ), and ozone (O 3 ) [15]
The interplay between autophagy and amino acid metabolism in cancer Amino acids as core regulatory signals of autophagy Autophagy is a conserved cellular degradation and recycling process that maintains energy homeostasis and cell survival by breaking down and reusing cellular components such as proteins and organelles [57]
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