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[4] These reactions may include pain, swelling, redness, or mild bruising at the site of the subcutaneous injection

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doi: 10.1681/ASN.2010080892 156 LyonsPARaynerTFTrivediSHolleJUWattsRAJayneDRet al

No loading or tapering is required for most protocols

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[118] Methionine synthase [edit] Methionine synthase, coded by MTR gene, is a methyltransferase enzyme which uses the MeB 12 and reaction type 2 to transfer a methyl group from 5-methyltetrahydrofolate to homocysteine, thereby generating tetrahydrofolate (THF) and methionine