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Gynecol Endocrinol 40(1):2382818 Zheng D, Liwinski T, Elinav E (2020a) Inflammasome activation and regulation: toward a better understanding of complex mechanisms

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135,191,192 While this seminal work focused mostly on DNA recognition and the mechanism of transcriptional regulation, these authors noted the presence of a potential metal binding motif, later shown to be critical for imparting metal selectivity ( vide infra )

Similar to anemia and leukopenia, an enlarged spleen can result in enhanced clearance/destruction of platelets (MedlinePlus 2012d)

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