Other uses include an add-on treatment for major depressive disorder, tic disorders, and irritability associated with ASD, as it shows a different mechanism of action from those of the other atypical antipsychotics (e.g., clozapine, and risperidone) by acting rather as a partial agonist on the D2Rs and 5-HT1A receptors (Marcus et al., 2009
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[DOI] [PMC free article] [PubMed] [Google Scholar] 161.Mattison J.A., Colman R.J., Beasley T.M., Allison D.B., Kemnitz J.W., Roth G.S., Ingram D.K., Weindruch R., de Cabo R., Anderson R.M
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