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PMID 31651033
What we do know from recent epidemiological evidence from the USA is that those who both vape and smoke are at an additional four-fold increased risk of developing lung cancer, said co-author Freddy Sitas, an epidemiologist at UNSW
This is partly due to the overlapping neurobiological mechanisms in addiction, where nicotine alters brain chemistry, accelerating the reward response system, which makes other substances more appealing
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Hilary Tindle, MD, PhD, the Founding Director of ViTAL, the Vanderbilt Center for Tobacco, Addiction, and Lifestyle at Vanderbilt University Medical Center, told Healthline that the research is invaluable and that she will use this Cochrane Review (including e-cigarette evidence) to update Smoking Cessation guidelines for patients with cancer