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It is one of the enzymes for cleavage-modification of -Syn, widely distributed in brain tissue and CSF, and mostly found in the form of 25 ku zymogen (Spencer et al., 2013)

Chang JY, Zhang Y, Zhu A, Welsh J, Gomez DR, Komaki R, Roth JA, Swisher SG

Furthermore, the crystal structure of the complex of GtmA and S-(5-adenosyl)-L-homocysteine combined with the molecular docking of gliotoxin and GtmA indicated that the methylation of the C10a-SH group precedes the alkylation of the C3-SH site in dithiol gliotoxin [108]

Imokawa G

We tested the passive uptake of the probe and followed its covalent conjugation to Halo-eGFP-BASU inside the cell (Fig