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In addition to lactobacilli , other bacterial species including Pseudomonas and Burkholderia , as well as bacterial metabolites such as butyrate, inhibit Candida yeast to hypha transition

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The analysis of cervicovaginal fluids highlighted a notable increase in the levels of IL-4 and IL-10 in women supplemented with ALA compared to placebo, while no significant changes in the levels of proinflammatory cytokines were observed between the groups

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This paradoxical improvement occurs because pain reduction outweighs any stimulatory effect on neurotransmitters

No adequate clinical safety programme was identified