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These effects result from the peptide's ability to activate multiple growth factor pathways simultaneously, including TGF-, basic fibroblast growth factor (bFGF), and insulin-like growth factor-1 (IGF-1)

Bushweller, J

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It has been reported that STAT3 can directly bind to NF-B and facilitate its nuclear translocation and target gene expression, suggesting that STAT3 is involved in the constitutive activation of NF-B (39)

This temporary effect is probably due to immune system activation, mediated by cytokines that interfere with the hypothalamo-pituitary-ovarian (HPO) axis

All results were averaged from at least three consecutive measurements