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Part of B cells in the synovial membrane differentiate into plasma cells to produce autoantibodies such as anti-citrulline protein antibody (ACPA), and the other part differentiate into effector B cells to produce proinflammatory cytokines, including IL-1, IL-6, IL-12, TNF-, and express RANKL

Non-enzymatic antioxidant (glutathione) levels A reduction in reduced glutathione (GSH) was observed in arthritic rats

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Antioxidants work at the cellular level for anti-aging benefits, including improvements to the skin and strengthening of the hair and nails

Efficacy and safety of total glucosides of paeony in the treatment of 5 types of inflammatory arthritis: A systematic review and meta-analysis