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Specifically, the researchers focused on immune cells in the lungs called alveolar macrophages (AMs)

they are found most abundantly in gene promoters and repetitive DNA elements

Current active smokers smoked at the time of the study or stopped smoking within six months (ex-active smokers quit at least six months prior)

Cigarette smoke contains numerous toxic chemicals, including tar and carbon monoxide, which wreak havoc on the delicate lung tissues