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In a murine model of melanoma overexpressing IL-12 (B16-IL-12), NKp46 + ILC3 were shown to infiltrate the tumor and mediate the upregulation of ICAM-1 and VCAM-1 adhesion molecules on tumor vessels leading to the generation of a pro-inflammatory microvascular environment (123)

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Davydov AI, Khabarova MB, Chilova RA, Lebedev VA, Shakhlamova MN

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Wu C, Chen X, Cai Y, Xia J, Zhou X, Xu S, et al