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Slides were then stained for MCP-1 and nitrotyrosine to assess inflammation and oxidative stress, respectively, using specific antibodies and an HRP-DAB cell and tissue staining kit (R&D Systems)

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Scientific Activity In receptor assays, cagrilintide activates calcitonin-family amylin receptors and the calcitonin receptor, coupling primarily to Gs and cyclic AMP signaling

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