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In line with this, one other mechanism recently described to be involved in the resistance to GSH depletion is the overexpression of deubiquitinases that inhibit protein degradation following ER-stress (74)

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Cardiolipin oxidized by ROS from complex II acts as a target of gasdermin D to drive mitochondrial pore and heart dysfunction in endotoxemia

Some protocols begin with a brief intensive phase (for example, daily or alternate-day dosing) followed by a maintenance phase (for example, weekly to monthly), particularly for B12 deficiency

A summary of data collection and refinement statistics for datasets of fragment complexes is shown in Supplementary Table 3