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Based on these observations, ebselen was concluded to be the GPx mimic

Based on these studies, it may be concluded that -synuclein is responsible for both the diminished activity of catalase and the increased formation of hydrogen peroxide, as substantiated by the increased oxidative stress markers in Parkinsons disease

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[DOI] [PMC free article] [PubMed] [Google Scholar] 43.Marletta A.S., Massarotti A., Orsomando G., Magni G., Rizzi M., Garavaglia S