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Post-injection timing around mechanical stimulus (resistance training) increases tissue-specific accumulation by 23 in activated muscle compared to rested tissue when dosed within 30 minutes post-exercise

Compounds absorbed here enter systemic circulation without passing through the hepatic portal system

PMID: 10199753 Houston J.B

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Thus, therapeutic targeting of senescent cells is feasible under conditions where loss of health has already occurred and in doing so tissue homeostasis can effectively be restored

PMID 15919781