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Wrong hormones The WHI used Premarin (conjugated equine estrogens from horse urine) plus Provera (synthetic progestin) not bioidentical hormones Wrong timing The average participant was 63 years old more than a decade past menopause

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Smaller volume, same dose

Recommended frequency: 1-2 times per week for initial course (5-10 sessions), followed by maintenance protocol (once every two weeks)

Selank can help stabilize enkephalins in the blood (Miller P, 2013)

Current serotonin medications are aimed at increasing central 5-HT neurotransmission in the brain, and there are no approved indications for manipulating peripheral 5-HT, though peripheral 5-HT synthesis is being considered as a potential target for developing pharmacological agents in some disorders ( We are not aware of prior studies reporting low S-5-HT in hypothyroidism or CFS