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It plays a crucial role in various bodily functions, including detoxification, immune response, and the maintenance of cellular health

Activation of trypsin induces the leakage of lysosomes and the release of cathepsin B into the cytoplasm, which activates the cell death pathway and finally causes pancreatic injury mainly in the forms of cellular apoptosis and necrosis 21

Honda et al

At this moment, treatments targeting the intestinal barrier in chronic liver disease are still lacking

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