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Hyodeoxycholic acid (HDCA) improves NAFLD via PPAR activation, inhibits abnormal nuclearcytoplasmic shuttling, and reduces lipid accumulation and oxidative stress (Zhong et al., 2023)

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ClinicalTrials.gov (2010) 7

The novel anti-cancer fluoropyrimidine NUC-3373 is a potent inhibitor of thymidylate synthase and an effective DNA-damaging agent

923 However, supplementation with exogenous PUFA to balance the PUFA/MUFA ratio increases the sensitivity of resistant tumors to ferroptosis