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The PD-1/PD-L1 pathway is a key immune checkpoint, and inhibiting PD-1/PD-L1 could improve clinical outcomes for cancer patients (Tiwari et al., 2022)

474 The addition of bevacizumab to chemotherapy benefits patients with metastatic breast cancer and those with stage II-III TNBC in the neoadjuvant settings

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Additionally, other issues, like liver disease, might become aggravated by fluctuating thyroid hormone levels, even when the liver cells are capable of handling their own levels of oxidative stress