On the other hand, Sesamin and Quercitrin showed a LD50 value of 1500 mg/kg and 5000 mg/kg respectively, which lied in the range of LD50 values exhibited by 4-Hydroxy PBN, NXY-059, NAC and PBN suggesting its potent role as an anti-oxidant along with a good MD simulation and Docking results
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Maintenance of cells and animals Ea.hy926 (E9) cells: E9 cells were purchased from National Centre for Cell Science (NCCS), Pune and maintained in Dulbeccos Modified Eagle Medium (DMEM) with 10% fetal bovine serum (FBS) and 1% antibiotic-antimycotic solution (Himedia, A002) (10,000 units of penicillin and 10 mg of streptomycin in 0.9% NaCl) in a humidified atmosphere with 5% CO 2 at 37 C
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Demar S, Kothari A, Calcutt NA, Fernyhough P
L.CincillaG.Snchez-MartnezM.et al (2022)