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A major challenge in translating preclinical data to clinical applications lies in the significant differences between animal models and human physiology, including variations in ovarian physiology, follicle dynamics, hormonal regulation, and drug metabolism can lead to divergent responses between rodents and humans
There are dietary differences between the industrialized and non-industrialized parts of the world
However, the model concentration of GSH declines in the fasting state about as rapidly as observed experimentally (See Section B, below)
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if uncontrolled, it might cause hypoglycemia [4]
