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Methimazole, an oral antithyroid medication which is a potent peroxidase and tyrosinase inhibitor, has shown depigmentation effects when applied topically and caused significant skin lightening in patients with melasma [75, 78, 96, 97]

Thirty-seven trials included in this literature review administered L-carnitine intravenously while 12 trials used oral L-carnitine (Chen 2014)

Researchers utilize this compound in cell cultures of fibroblasts and other dermal cells to explore its influence on gene expression related to tissue repair and inflammatory pathways

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Patients with significant anaemia require monitoring of serum potassium, particularly during loading doses