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Introduction Traumatic brain injury (TBI) is a general term for pathological or structural changes in the brain caused by impact, bumps, penetrating injuries, or blasting under external forces ( In the acute phase, moderate and severe TBI often cause intracranial hemorrhage, and half of the TBI patients may suffer from traumatic cerebral hemorrhage in addition to the primitive hematoma that causes compressive damage to brain tissue (Rosenfeld et al., 2012)

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Safaei F, Mehrzadi S, Khadem Haghighian H, Hosseinzadeh A, Nesari A, Dolatshahi M, et al Protective effects of gallic acid against methotrexate-induced toxicity in rats Acta Chir Belg

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