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With the increasing prevalence of AD due to rising life expectancy, basic and clinical studies have become more crucial to uncovering the mechanisms underlying its pathogenesis and developing effective treatment strategies, not only for AD but also for other brain disorders 5

Conclusion This systematic review found that glutamine supplementation can lead to a decrease in fasting blood glucose, post-meal glucose, and triglyceride levels and an increase in insulin production

Finally, an imbalance in GSSG:GSH ratio induces ER stress and dependency on the ER-associated degradation (ERAD) pathway, driven by a shift in protein disulfide isomerases (PDIs) toward their oxidized forms

(Cham: Springer International Publishing), 257270

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Int J Nutr 134:489492 Xiao Z, La Fontaine S, Bush AI, Wedd AG (2019) Molecular mechanisms of glutaredoxin enzymes: versatile hubs for thiol-disulfide exchange between protein thiols and glutathione