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It also indirectly regulates the immune system by inhibiting PGE2 synthesis, potentially aiding in HPV prevention [193]

8.3 Other potential indications Besides bronchiectasis and COPD, DPP1 inhibitors have shown important application potential in research for various other indications

Marklund S, Marklund G (1974) Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase

In addition to the scarcity of human studies testing Hx replenishment as a therapeutic in SCD, another foreseeable limitation of this strategy is the cost

PGAM5-mediated mitophagy also inhibits necroptosis and protects cells from proinflammatory effects 12

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