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Neo-B12 Injection is used to treat pernicious anaemia, which is a condition where there are insufficient red blood cells carrying haemoglobin, which remain as immature precursor cells

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There arent any official medical guidelines about who should get a coffee enema

The rate of 0.25 mg/kg/h is maintained for 6 hours to assess for side effects before further dose increases up to a maximum rate of 1 mg/kg/h infused continuously for a maximum of 5 days

Link Ruxton, C