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In a co-culture model comprising neurons, astrocytes, and microglia derived from human induced pluripotent stem cells, exposure to iron and the ferroptosis inducer RSL3 demonstrated that microglia were the most susceptible to iron overload

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The pronounced IgG2a/c responses are consistent with IFN--driven class switching, supporting T-cell-dependent pathways that contribute to humoral immunity ( Pf CSP and Pb SLTRiP