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After moving through the basolateral membrane, zinc primarily binds to the circulating protein albumin3

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3.2.2 BNIP3/NIX mediated mitophagy NIX, a protein with 50% homology to BNIP3 (Matsushima et al., 1998), binds to the mitochondrial outer membrane through its carboxyl transmembrane domain, thereby initiating mitophagy under ischemic or hypoxic conditions