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These include TNF-alpha, IL-1 beta, and IL-6, all of which drive joint destruction in inflammatory arthritis

Many registered phase I/II clinical trials designed to investigate the effectiveness of curcumin alone or with first-line treatment in patients with breast, prostate, pancreatic, lung, or colorectal cancer are under way (69)

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C., Cariello, N

In contrast, Western-style dietary patterns high in fat, calories, and red meat may negatively affect thyroid health, while gluten-free or lactose-free regimens do not appear to provide significant benefits

Blue curcuma was investigated for the presence of azulenes (conjugated 5- and 7-membered fused ring system) that is known to impart bluish coloration