The broader picture is that the next generation of obesity treatments involves multi-target approaches, whether through single molecules activating multiple receptors (tirzepatide, retatrutide, survodutide, mazdutide) or through combination therapies pairing separate compounds (CagriSema)
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De Bock, K., Cauwenberghs, S., & Carmeliet, P
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Specifically, certain studies have investigated its capacity to upregulate growth hormone receptors (GHR), which could theoretically sensitize tissues to existing GH levels and enhance downstream anabolic processes
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