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Papo N, Shahar M, Eisenbach L, Shai Y

Tissue homeostasis under stress promoting stability and repair in tissues exposed to injury, overuse, or oxidative stress*

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Giannoulis MG, Sonksen PH, Umpleby M, et al

[7] Increased pressure within the abdomen caused by: Heavy lifting or bending over Frequent or hard coughing Hard sneezing Violent vomiting Straining during defecation (i.e., the Valsalva maneuver) Obesity and age-related changes to the diaphragm are also general risk factors

Once phosphorylated, FOXO4 translocates to the nucleusthe command center of the cell