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It is sold as a research compound

Route, quality, formulation, dosing clarity, storage, medical oversight, and follow-up all matter

Therapeutic dosing usually involves Vitamin B12 doses of 1000 mcg or more per day

A deficiency can affect the nervous system and cause sensations such as numbness or tingling in the hands, feet, or legs

A deficiency of CD4+CD25+ T cells permits the development of spontaneous lupus-like disease in mice, and can be reversed by induction of mucosal tolerance to histone peptide autoantigen

Some individuals prefer the natural version because it matches what already exists in the human body