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However, due to factors such as diet, age, or other medical conditions, some individuals may struggle to get enough B12 from their diet alone

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62 Two double-blind RCTs investigated the effectiveness of B12 in adults who had been suffering from low back pain for more than 6 months, and both found significantly better pain reduction in the B12 compared with the placebo group

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Thus, the discovery of liver juice as a treatment for pernicious anemia had been by coincidence