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The circulating levels of RELM- are increased in obese db/db mice and by feeding mice a high-fat diet (133)

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Despite promising results in AML therapy, up to one third of patients is refractory to Venetoclax-based therapy, and resistance often develops within one year of treatment 12 , necessitating studies of cellular mechanisms that modulate Venetoclax responsiveness

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Taking Prince George, British Columbia, Canada as an illustrative case, we draw on archival sources and spatial analysis of historical subdivision data