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InTech Kruk JS, Vasefi MS, Heikkila JJ, Beazely MA (2013) Reactive oxygen species are required for 5-HT-induced transactivation of neuronal platelet-derived growth factor and TrkB receptors, but not for ERK1/2 activation

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1.0 0.5 mmol/L, p 300 mg/g as macroalbuminurea, or 30 mg/g as microalbuminuria in at least two out of three consecutive urine collections/morning urine samples (PROLONG-Denmark, DIALONG) or based on a documented diagnosis of diabetic kidney disease (PROLONG-Sweden)

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A prospective follow-up of DILI patients in the Spanish hepatotoxicity registry showed a 5% incidence of chronic DILI