J., Kang, S
Excessive production of ROS in the brain can lead to the oxidation of proteins, lipids, and nucleic acids, resulting in cellular dysfunction and death [13,14,15,18,20,28]
Among the 268 glycerophospholipids, 22 species were significantly upregulated, while 60 species were downregulated
At first, they found that cfDNA and cGAS expression in lymph nodes or spleen from CIA mice and RA patients were upregulated
In this context, ineffective immune control of EBV-transformed B cells that stimulate autoreactive T-cell responses could facilitate both the initial activation of cross-reactive T cells and their local re-stimulation by EBV-infected B cells, thus promoting autoimmunity in the CNS of patients with multiple sclerosis (300)

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