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Odevixibat, a small molecule that inhibits ileal resorption of BAs belonging to the class of ileal BAs transporter (IBAT) inhibitors, was the first drug approved for the treatment of PFIC patients 6 months old due to its efficacy on both pruritus and reduction of serum BAs as well as its good tolerability in 2021 [16]

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Journal of Experimental Medicine

These findings are similar to ours in that the 5-HT confers protection against a hepatic injury by promoting the hepatocyte proliferation and liver regeneration by the activation of 5-HT 2B receptor

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Rheumatoid Arthritis: A Brief Overview of the Treatment