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This is where the neuroprotective properties of pineal peptides become relevant

These substances are classified as cognitive substances that primarily affect cholinergic transmission in the brain rather than nootropics [158], so only their well-known representative, phosphatidylcholine (lecithin), is described in more detail

Growth Horm IGF Res., 2001

Needles with a sharp, well-designed bevel reduce pain and trauma during insertion

Hyperglycemia leads to the activation of the pathways and the production of reactive oxygen species, and the increase of cytokines and chemokines such as IL-6 (interleukin 6), MCP-1 (monocyte chemoattractant protein-1), TGF- (transforming growth factor-), and VEGF (vascular endothelial growth factor) leads to inflammation, fibrosis, and increased vascular permeability [22]

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