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Many trials have assessed the effect of B vitamin supplements and homocysteine-lowering on stroke outcomes, with mixed results

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Researchers have proposed several mechanisms, including direct effects on gene transcription factors and indirect influences through cellular signaling cascades that regulate telomerase activity

Wu M, Wu J, Liu K, Jiang M, Xie F, Yin X, et al

Additionally, apremilast exhibited good tolerability, with a favorable safety profile characterized by mild-to-moderate adverse events, such as gastrointestinal symptoms, which were generally transient and manageable (Ohtsuki et al

They aimed to predict iROA diagnosis one year prior to its occurrence