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IGF-1Ec (MGF, or Mechano Growth Factor) A local growth factor rapidly produced in muscle after mechanical stress or injury

IF also confers a protective effect against oxidative stress and inflammation by activating antistress responses, including nuclear respiratory factor (Nrf)-1, Nrf-2 and mammalian target of rapamycin (mTOR) pathways [16, 17]

The nuclear factor erythroid 2-related factor 2 ( NFE2L2 or NRF2) transcription factor is constitutively activated in many cancers and promotes a specific gene expression program involved in cellular detoxification, redox buffering, and metabolic rewiring (Cancer Genome Atlas Research, 2012

In the presence of GSH, GPX4 reduces the accumulation of lipid peroxidation

Munita JM, Arias CA

PT-141: May regulate dopamine production, boost sexual arousal and performance