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With regards to postmortem diagnostics in AD, more generalized approaches could be more routinely taken such as metagenomic sequencing to identify all microbes present in the plaques, or else alginate staining to detect biofilms that could be from a variety of sources

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Indeed, both behavioral hyperactivity and specifically autophagic neuron death are caused by the sleep-restricting drug cocaine via an nNOS nitrosylation-mediated co-transmission pathway (Xu et al., 2013

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