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The Ghost Trial In the late 1990s and early 2000s, the Croatian pharmaceutical company Pliva sponsored clinical trials for BPC-157 as a treatment for inflammatory bowel disease

This combination helps decrease free radicals and boos production of glutathione and other antioxidants in the body

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(10 g or 10 ng/kg/day), topical (1.0 g in cream), or per-oral (0.16 g/mL in drinking water) over 90 days and described directional improvements across biomechanical, functional, macroscopic, and histological endpoints, though specific effect sizes and p-values are not reported in the abstract

Furthermore, the expression of MMP2 and MMP9 downregulated while the expression of TIMP1 increased