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DJ-1 binds to subunits of mitochondrial complex I and regulates its activity (Zhang et al., 2005), the degree of translocation of DJ-1 into mitochondria is stimulated by oxidative stress (Junn et al., 2009)
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6,409,410 During a previous experiment, researchers induced pain and observed symptoms of cognitive impairment in rats through spinal nerve ligation
however, cadherin/catenin interaction, as AJ proteins, regulate cell-cell adhesion between endothelial cells, contributing to the overall junction arrangement and BBB integrity (Li et al., 2019)