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Bioavailability refers to the proportion of a nutrient that actually enters your bloodstream and is used by your cells

However, neurotrophins have had little success in clinical trials directed at neurodegenerative diseases due to their poor pharmokinetic profile and large molecular weight that significantly impedes penetration of the BBB [61,62]

Researchers study these peptides in preclinical models involving tissue repair, angiogenesis, inflammatory response, and recovery-related biological pathways

The preclinical research is not trivial, and legitimate questions about potential applications in tendon repair, gut healing, and neuroprotection merit serious investigation

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