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Interestingly, structure of an inhibitor of ACh esterase, acotiamide (brand name acofide), approved in Japan as a prokinetic motility drug against functional dyspepsia (216218), combines the two heterocycles, one of them thiazole, that may be considered as structural mimics of the thiazolium and aminopyrimidine heterocycles of thiamine

Walsh et al

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KPV (10mg) is a tripeptide composed of lysine, proline, and valine, derived from the C-terminal end of alpha-melanocyte-stimulating hormone (alpha-MSH)

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